Takatsukasa Fusasuke (?? ??, June 22, 1637 – March 1, 1700), son of Norihira, was a Kugyo or Japanese court noble of the early Edo period (1603–1868).
He held regent positions sessho (from 1664 to 1668) and kampaku (from 1668 to 1682).
Kanehiro and Sukenobu were his sons who he had with a daughter of the second head of the Choshu Domain Mori Hidenari.