Charles Édouard Guillaume (15 February 1861, in Fleurier, Switzerland – 13 May 1938, in Sèvres, France) was a Swiss physicist who received the Nobel Prize in Physics in 1920 in recognition of the service he had rendered to precision measurements in physics by his discovery of anomalies in nickel steel alloys.
In 1919, he gave the fifth Guthrie Lecture at the Institute of Physics in London with the title "The Anomaly of the Nickel-Steels".