Nicolae Constantin Paulescu (Romanian pronunciation: [niko'la.e pa.u'lesku]; 30 October 1869 (O.S.) – 17 July 1931) was a Romanian physiologist, professor of medicine, and politician, most famous for his work on diabetes, including patenting pancreine (a pancreatic extract containing insulin).
The "pancreine" was an extract of bovine pancreas in salted water, after which some impurites were removed with hydrochloric acid and sodium hydroxide.
Paulescu was also, with A.
Cuza, co-founder of the National Christian Union and later, of the National-Christian Defense League in Romania.