Isao Kiso (?? ?, Isao Kiso, born 11 February 1952) is a Special Advisor to the Cabinet and a former official of the Ministry of Education, Culture, Sports, Science and Technology in Japan.
He has held positions as the Director of Cultural Properties Department at the Agency for Cultural Affairs, the Head of Minister’s Secretariat International Affairs Division at the Ministry of Education, Culture, Sports, Science and Technology, and the Ambassador Extraordinary and Plenipotentiary of Japan, Permanent Delegate to UNESCO.