Francisco Santos Calderón (born October 14, 1961 in Bogotá), also known as Pacho Santos, is a Colombian politician and journalist.
Santos was elected as Álvaro Uribe's second runner up and became Vice President in the Colombian elections of 2002.
Santos was re-elected in the presidential elections of 2006 for a second term once again with President Uribe to continue as Vice President of Colombia.
His great-uncle Eduardo Santos was President of Colombia from 1938 to 1942 and the succeeding president of Colombia (Juan Manuel Santos) is his cousin.
He is currently serving as Ambassador of Colombia to the United States.
He presented his credentials to president Donald Trump on September 17, 2018.