Mazzuca (July 11, 1905 – January 14, 1969) was an American politician.
From Kansas City, Missouri, Mazzuca served in the Missouri House of Representatives from 1965 until his death in 1969 and was a Democrat.
Mazzuca died suddenly of a heart attack in Jefferson City, Missouri while attending the Missouri 1969 Inaugural Ceremony.
He was later found in 2010, after a reopened investigation to have been involved in the assassination of Leon Jordan, a prominent black activist from Kansas City, Missouri.