Elisa Frota Pessoa, born Elisa Esther Habbema de Maia (17 January 1921 – 28 December 2018), was a Brazilian experimental physicist.
She was one of the first women to graduate in physics in Brazil, in 1942, and a founding member of the Centro Brasileiro de Pesquisas FÃsicas (Brazilian Center of Physical Research).
She was distinguished by her studies of radioactivity with nuclear emulsions; reactions and disintegrations of K and p mesons in nuclear emulsions; and reactions of protons and deuterons with nuclei of average masses.