John Mitchell (April 13, 1711 – February 29, 1768) was a colonial American physician and botanist.
He created the most comprehensive and perhaps largest 18th-century map of eastern North America, known today as the Mitchell Map.
First published in 1755, in conjunction with the imminent Seven Years' War, the Mitchell Map was subsequently used during the Treaty of Paris (1783) to define the boundaries of the newly independent United States and remains important today for resolving border disputes.