Yosef Gruenbaum (born September 22, 1949) (Hebrew: ???? ?????????) is an Israeli researcher, academic, biochemist and professor in medicine based in Jerusalem, Israel.
He is known for his research on nuclear lamins and their associated proteins in health and disease.
He is the Chairman of the Silberman Institute of Life Sciences at the Hebrew University of Jerusalem and an adjunct professor at the Northwestern University, Chicago.