After his PhD he taught at Catholic University of America and specialized in the study of the electrical properties of solid matter.
Back in France he was nominated Professor in charge of the Electromagnetism Chair at ESPCI Paris where Georges Charpak arrived in 1980.
In 1987 Pierre-Gilles de Gennes asks him to become Scientific Director of ESPCI Paris, a position he will keep until 2001.
His works have been devoted to electrical insulators and particularly electrets, instrumentation and sensors, for instance in medical imaging, or on the improvement of telecommunication networks.
Jacques Lewiner has filed a large number of patent applications leading to industrial development, either through licenses granted to industrial companies or through start-up companies often created with former students or researchers.
Most of these companies have experienced a strong growth.
For instance Inventel, which was the French leader for multimedia gateways was bought by Thomson SA in 2005.
With Jean-Louis Viovy he created Fluigent which develops fluid motion systems for micro-fluidic applications.
Jacques Lewiner is laureate of the French Academy of Sciences in 1990, Knight in the National Order of the Legion of Honor, member of the French Academy of Technologies since 2005, Honorary Fellow of the Technion, Doctor Honoris Causa from Ben Gurion University of the Negev, Doctor Honoris Causa from Technion.
In 2017 he has received the Marius Lavet Special Prize.