His group studied liquid crystal and soft matter properties.
In 1996, he founded the group "Physical Chemistry Curie" lab at the Curie Institute (Paris).
His group studies physical approaches to biological problems and describes cell motion, molecular motors, the properties of biological membranes and protein adhesion.
Jacques Prost was the scientific advisor to Elf Aquitaine from 1990 to 1999.
He is a member of the French Academy of Sciences since 2007.
Jacques Prost has been the General director of ESPCI ParisTech, since 2003.