Marie-Hélène Lefaucheux (26 February 1904 – 25 February 1964) was a French women's and human rights activist.
During World War II, she was a member of the French Resistance and orchestrated her husband's release from Buchenwald concentration camp after he was captured by the Gestapo.
She was the sole woman in the French delegation to the first General Assembly of the United Nations.
Lefaucheux helped found the UN's Commission on the Status of Women and was its chair from 1948 to 1953.