Tokugawa Shigeyoshi (?? ??, March 17, 1745 – August 22, 1795) was a Japanese samurai of the mid-Edo period who was the founder of the Shimizu-Tokugawa family, one of the Gosankyo, the three lesser branches of the Tokugawa family.
He was the second son of Tokugawa Ieshige, the ninth shogun.
His child-hood name was Manjiro (???).
He married daughter of Prince Fushimi no Miya Sadatake.