Alexander Rich, Date of Birth, Place of Birth, Date of Death

    

Alexander Rich

American biologist, biophysicist

Date of Birth: 15-Nov-1924

Place of Birth: Hartford, Connecticut, United States

Date of Death: 27-Apr-2015

Profession: biophysicist, molecular biologist

Nationality: United States

Zodiac Sign: Scorpio


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About Alexander Rich

  • Alexander Rich (November 15, 1924 – April 27, 2015) was an American biologist and biophysicist.
  • He was the William Thompson Sedgwick Professor of Biophysics at MIT (since 1958) and Harvard Medical School.
  • Dr.
  • Rich earned both an A.B.
  • (magna cum laude) and an M.D.
  • (cum laude) from Harvard University.
  • He was a post-doc of Linus Pauling along with James Watson.
  • During this time he was a member of the RNA Tie Club, a social and discussion group which attacked the question of how DNA encodes proteins.
  • He had over 600 publications to his name. Born in Hartford, Connecticut, Rich was the founder of Alkermes and was a director beginning in 1987.
  • Dr.
  • Rich was Co-Chairman of the Board of Directors of Repligen Corporation, a biopharmaceutical company.
  • He was also a member of the Board of Directors for Profectus BioSciences, Inc.
  • He also served on the editorial board of Genomics and the Journal of Biomolecular Structure and Dynamics. In 1963, Rich discovered polysomes: clusters of ribosomes which read one strand of mRNA simultaneously.In 1973, Rich's lab determined the structure of tRNA.In 1979, Rich and co-workers at MIT grew a crystal of Z-DNA.
  • This was the first crystal structure of any form of DNA.
  • After 26 years of attempts, Rich et al.
  • finally crystallised the junction box of B- and Z-DNA.
  • Their results were published in an October 2005 Nature journal.
  • Whenever Z-DNA forms, there must be two junction boxes that allow the flip back to the canonical B-form of DNA.
  • Rich died on April 27, 2015, aged 90.Rich was married to Jane King and is survived by four children: Benjamin, Josiah, Rebecca, and Jessica Rich Sturley.

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