Caleb Willoughby Shaffner (February 3, 1845 – August 15, 1932) was a travelling salesman and political figure in Nova Scotia, Canada.
He represented Annapolis County in the Nova Scotia House of Assembly from 1878 to 1882 as a Conservative member.
He was born in Nicteaux, Annapolis County, Nova Scotia, of German descent, and was educated at Acadia College.