Dejan Karaklajic (born 1 May 1946 in Belgrade) is a Serbian television and film director.
Karaklajic was active from the late 1960s through to the early 1980s and mainly worked on television films made by Radiotelevizija Beograd (today called Radio Television of Serbia).
He also directed two feature films, Beloved Love (Ljubavni život Budimira Trajkovica, 1977; starring Milena Dravic and Ljubiša Samardžic) and Erogenous Zone (Erogena zona, 1981).