He is the Joseph and Ceil Mazer Professor Emeritus of History and Philosophy of Science, and Director of the Center for Religious and Interreligious Studies at Tel Aviv University.
He is also Senior Fellow of the Goethe University's Forschungskolleg Humanwisseschaften.Fisch has published widely on the history of 19th century British science and mathematics, on confirmation theory and rationality, on the theology of the talmudic literature, and the philosophy of talmudic legal reasoning.
In recent work he explores the limits of normative self-criticism, the Talmud's dispute of religiosity, the historiography and narratology of scientific framework transitions, and the possibility of articulating a pluralist political philosophy from within the assumptions of halakhic Judaism.
Fisch has been a Member of the Institute for Advanced Study, Princeton, Fellow of the Wissenshaftskolleg, the Berlin Institute for Advanced Study and the Dibner Institute for the History of Science and Technology, MIT, Senior Visiting Fellow at Collegium Budapest, Visiting Scholar at Trinity College, Cambridge, and was a long term Senior Research Fellow at the Shalom Hartman Institute, Jerusalem.