Locke (August 3, 1898 – November 9, 1969) was an American football player and coach.
He played college football at the University of Iowa, where he was a two-time All-American.
Locke served as the head football coach at Western Reserve University—now a part of Case Western Reserve University—from 1926 to 1930, compiling a record of 15–20–1.
He was inducted into the College Football Hall of Fame as a player in 1960.