Jessica-Jane Applegate MBE (born 22 August 1996) is a British Paralympic swimmer.
Applegate competes in the S14 classification for swimmers with intellectual disabilities, mainly freestyle and backstroke preferring shorter distances.
She qualified for the 2012 Summer Paralympics and on 2 September in the S14 200m freestyle, Applegate won the gold setting a Paralympic record.
She was appointed Member of the Order of the British Empire (MBE) in the 2013 New Year Honours for services to swimming.