In 1580 he married Ana de la Cueva, daughter of Don Gabriel de la Cueva, 5th Duke of Alburquerque with whom he had one daughter.
On 21 August 1606, he married for a second time, with Antonia de Toledo y Dávila, daughter of Don Gómez Dávila, 2nd Marquis of Velada and tutor of King Philip III of Spain, with whom he had one son.