Mary Fisher (born April 6, 1948) is an American political activist, artist and author.
After contracting HIV from her second husband, she has become an outspoken HIV/AIDS activist for the prevention, education and for the compassionate treatment of people with HIV and AIDS.
She is particularly noted for speeches before two Republican Conventions: Houston in 1992 and San Diego in 1996.
The 1992 speech has been hailed as "one of the best American speeches of the 20th Century."She is the founder of a non-profit organization to fund HIV/AIDS research and education, the Mary Fisher Clinical AIDS Research and Education (CARE) Fund.
Since May 2006, she has been a global emissary for the Joint United Nations Programme on HIV/AIDS (UNAIDS).