Panagis Tsaldaris (also Panagiotis Tsaldaris or Panayotis Tsaldaris; Greek: ?a?a???t?? (?a?a???) ?sa?d????; 5 March 1868 – 17 May 1936) was a Greek politician and the 48th Prime Minister of Greece.
He was a revered conservative politician and leader for many years (1922–1936) of the conservative People's Party in the period before World War II.
He was the husband of Lina Tsaldari, a Greek suffragist, member of Parliament, and the Minister for Social Welfare.