Lesley Phuti Manyathela (4 September 1981 – 9 August 2003) was a South African professional footballer who played as a striker for Premier Soccer League club Orlando Pirates and the South African national team.
A prolific goalscorer, Manyathela scored 48 goals in 73 appearances for Orlando Pirates and was the league's top goalscorer in 2003.
Later that year, he was involved in a car accident which resulted in his death, aged 21.
Following his death, the PSL award for the top goalscorer was renamed the Lesley Manyathela Golden Boot in his honour and the national team temporarily retired the number 19 jersey which he had previously worn.