Date Yoshikuni (?? ??, October 17, 1825 – July 12, 1874) was a late-Edo period Japanese samurai, and the 13th daimyo of Sendai Domain in the Tohoku region of northern Japan, the 29th hereditary chieftain of the Date clan.
He is known primarily for his role as commander-in-chief of the Ouetsu Reppan Domei during the Boshin War of the Meiji Restoration.
During his tenure he was also known by his courtesy title, Mutsu no Kami (???).