Pavel Klhufek (born October 27, 1991) is a Czech professional ice hockey player who currently plays for HC Košice of the Tipsport Liga.
Klhufek began his career with his hometown HC Zlín, playing in their junior teams before joining HC Slavia Praha in 2009.
He made his Czech Extraliga debut for Slavia Praha during the 2010-11 season.
Klhufek would spend the next four seasons dividing his time between Slavia Praha and loan spells with HC Berounští Medvedi and BK Havlíckuv Brod until January 30, 2015 where he signed for Orli Znojmo of the Erste Bank Eishockey Liga.On June 5, 2017, Klhufek returned to Zlín, eight years after leaving their junior team.