Issam Merdassi (Arabic: ???? ????????) (born 16 March 1981) is a Tunisian footballer.
He currently plays for BSC Young Boys.
Merdassi played until 2006 for CS Sfaxien then went on loan to Saudi Al-Nassr before returning to CS Sfaxien for one saison 2008-2009 and finally he was transferred to BSC Young Boys in summer 2009.
He was a member of the Tunisian 2004 Olympic football team, who exited in the first round, finishing third in group C, behind group and gold medal winners Argentina and runners-up Australia.