In 1967, she was the first person of color and the first woman elected to the senate.
During her term, she was "regarded as the leading advocate for blacks, women, children, the poor, and the handicapped," and was the chair of the Health and Welfare committee from 1970-76 and the Labor and Industry committee from 1978-88.Powers attended the Louisville Municipal College, worked for organizations concerning civil and equal rights, and received an honorary doctorates from the University of Kentucky and the University of Louisville, among other honors.